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Various environmental (exposure to tobacco adverts), social (tobacco use by peers or family), genetic (genes associated with dopaminergic neurotransmitter system, cellular transport system or serotonergic neurotransmitter system, among others) and psychological factors were previously related to smoking and smoking addiction [4,5,6,7,8]

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[13] People with COPD often die as a result of comorbidities rather than from respiratory problems